Evidence Highlight

Pelvic Oncology

Author: Alexandra Hill, PT, DPT, CLT-LANA  Board-Certified Clinical Specialist in Oncologic Physical Therapy, Board-Certified Women's Health Clinical Specialist

Published January 1, 2026

What You Need to Know 

Pelvic health physical therapy is essential for people living with and beyond cancer (PLWBC), especially those with pelvic cancers. Compared to the general population, PLWBC face higher rates of pelvic floor disorders (PFD), which can arise during any phase of cancer care.

Key Points: 

  • PFDs can include bladder/bowel dysfunction, pelvic pain, prolapse, and sexual dysfunction.

  • Early, multimodal PT—including prehabilitation—improves outcomes and reduces long-term effects.

  • Breast, lung and stem cell transplant survivors also experience high rates of PFD, highlighting the need for broad screening beyond pelvic cancers.

  • Special considerations include lymphedema, surgical/radiation changes, psychological impacts, and age-specific needs.

Insights from the Literature: Oncology and Pelvic Floor Physical Therapy

Over 18 million Americans are living with a history of cancer, with pelvic cancers among the most common. People living with and beyond cancer (PLWBC) experience significantly higher rates of pelvic floor disorders (PFD), including bladder, bowel, and sexual dysfunction. These issues may arise during diagnosis, treatment, or years later.

Pelvic health physical therapy offers critical support through tailored, multimodal care—ranging from prehabilitation to manual therapy, exercise, and behavioral strategies. Survivors of breast, lung, and other cancers also face high rates of PFD, underscoring the need for broad screening. Special considerations include lymphedema, anatomical changes, psychological impacts, and the unique needs of adolescents and young adults. Early referral improves outcomes and reduces long-term burden.

As of January 2025, more than 18 million people in the U.S. were living with a history of cancer, a number projected to exceed 22 million by 2035.(Wagle et al., 2025) Among these, pelvic cancers, including prostate, colorectal, and uterine, are among the most prevalent diagnoses.(Wagle et al., 2025) Pelvic floor disorders (PFD) such as bladder and bowel dysfunction, pelvic pain, pelvic organ prolapse, and sexual dysfunction, are common in People Living With and Beyond Cancer (PLWBC), particularly those with pelvic cancers. Compared to the general population, PLWBC experience a substantially higher prevalence and severity of PFD. (Emanu et al., 2016; Ramaseshan et al., 2018; Colombage et al., 2022; Zhu et al., 2023; Shan et al., 2023). 

PFD among cancer survivors can be influenced not only by the type and combination of treatments received, but also by the cancer itself. (Neron et al., 2019). Pelvic health concerns can develop at any point along the care continuum, from diagnosis through acute care, long-term recovery, and late effects experienced months or years after treatment. The growing number of PLWBC experiencing PFD indicates the critical need for pelvic health physical therapists trained in this specialty area.  

Although pelvic health physical therapy interventions vary depending on the cancer diagnosis, stage of survivorship, and treatments received, early and multimodal rehabilitation is recommended to address PFD among PLWBC.( Cyr et al., 2024) Prehabilitation, for example, can improve functional performance, reduce treatment side effects, enhance outcomes, and address pre-existing pelvic floor symptoms, and it is increasingly integrated into pelvic oncology care pathways.(Gennuso et al., 2024)   Across the survivorship continuum, pelvic health physical therapy interventions often include education and behavioral strategies such as bladder and bowel retraining, pelvic floor muscle training (PFMT), electrical modalities, progressive therapeutic exercise, manual therapy for scars and radiation fibrosis, and training in the use of supportive devices such as vaginal or rectal dilators and vacuum erection devices.( Cyr et al., 2024; Bakker et al., 2014; Baumann et al., 2022 ; Zeng & Wang, 2024 ; Tim & Mazur-Bialy, 2023 ; Matos et al., 2019 ; Wolin et al., 2012 ; Cyr et al., 2022 ; Shu et al., 2025).

Although the rates of PFD among PLWBC are highest among those with pelvic cancers, breast cancer survivors also experience high rates of PFD and sexual dysfunction, with up to 90% of breast cancer survivors reporting sexual dysfunction. (Vitorino et al., 2024; Agrawal et al., 2025). Similarly, lung cancer survivors and stem cell transplant recipients have higher rates of PFD and sexual dysfunction compared to the general population, (Agrawal et al., 2025) highlighting the importance of screening beyond only pelvic cancers. Additional special considerations for pelvic cancer includes development of pelvic cancer-related lymphedema from cancer and cancer treatment, which necessitates the need to collaborate with a Certified Lymphedema Therapist (CLT),( Facondo et al., 2025; Hayes et al., 2017) anatomical changes from pelvic surgery and radiation therapy (e.g., fibrosis/stenosis impacting exams, continence, and sexual activity),( Raj et al., 2024) psychological sequelae (body image and intimacy),( Bowie et al., 2022; Plinsinga et al., 2024) and the unique needs of adolescents and young adults (sexual development, fertility, identity, and school/work participation).( Sopfe et al., 2020; Janssen et al., 2025).

References
Expand List of References
  • Wagle NS, Nogueira L, Devasia TP, et al. Cancer treatment and survivorship statistics, 2025. CA Cancer J Clin. 2025;75(4):308-340. doi:10.3322/caac.70011 
  • Emanu JC, Avildsen IK, Nelson CJ. Erectile dysfunction after radical prostatectomy: prevalence, medical treatments, and psychosocial interventions. Curr Opin Support Palliat Care. 2016;10(1):102-107. doi:10.1097/SPC.0000000000000195 
  • Ramaseshan AS, Felton J, Roque D, Rao G, Shipper AG, Sanses TVD. Pelvic floor disorders in women with gynecologic malignancies: a systematic review. Int Urogynecol J. 2018; 29(4): 459–476. doi:10.1007/s00192-017-3467-4
  • Colombage UN, Soh SE, Lin KY, et al. Occurrence and impact of pelvic floor dysfunction in women with and without breast cancer: a cross-sectional study. Braz J Phys Ther. 2022;26(6):100455. doi:10.1016/j.bjpt.2022.100455 
  • Zhu L, Li X, Zhou C, Tong Y, Liu Z, Huang C. Pelvic floor dysfunction after colorectal cancer treatment is related to physical and psychological health and body image: A cross-sectional study. Eur J Oncol Nurs. 2023;67:102425. doi:10.1016/j.ejon.2023.102425 
  • Shan X, Qian M, Wang L, Liu X. Prevalence of pelvic floor dysfunction and sexual dysfunction in cervical cancer survivors: a systematic review and meta-analysis. Int Urogynecol J. 2023;34(3):655-664. doi:10.1007/s00192-022-05326-y 
  • Neron M, Bastide S, Tayrac R, et al. Impact of gynecologic cancer on pelvic floor disorder symptoms and quality of life: an observational study. Sci Rep. 2019;9(1):2250. Published 2019 Feb 19. doi:10.1038/s41598-019-38759-5  
  • Cyr MP, Jones T, Brennen R, Colombage U, Frawley HC. Effectiveness of Pelvic Floor Muscle and Education-Based Therapies on Bladder, Bowel, Vaginal, Sexual, Psychological Function, Quality of Life, and Pelvic Floor Muscle Function in Females Treated for Gynecological Cancer: A Systematic Review. Curr Oncol Rep. 2024;26(11):1293-1320. doi:10.1007/s11912-024-01586-7 
  • Gennuso D, Baldelli A, Gigli L, et al. Efficacy of Prehabilitation in cancer patients: an Rcts systematic review with meta-analysis. BMC Cancer. 2024;24(1):1302. Published 2024 Oct 22. doi:10.1186/s12885-024-13023-w 
  • Bakker RM, ter Kuile MM, Vermeer WM, Nout RA, Mens JW, van Doorn LC, et al. Sexual rehabilitation after pelvic radiotherapy and vaginal dilator use: consensus using the Delphi method. Int J Gynecol Cancer. 2014;24:1499–506. 10.1097/IGC.0000000000000253 
  • Baumann FT, Reimer N, Gockeln T, et al. Supervised pelvic floor muscle exercise is more effective than unsupervised pelvic floor muscle exercise at improving urinary incontinence in prostate cancer patients following radical prostatectomy - a systematic review and meta-analysis. Disabil Rehabil. 2022;44(19):5374-5385. doi:10.1080/09638288.2021.1937717 
  • Zeng Y, Wang J. Pelvic Floor Muscle Exercises can Effectively Improve Urinary Incontinence after Radical Prostatectomy: Systematic Review and Meta-Analysis Based on Randomised Controlled Trials. Arch Esp Urol. 2024;77(6):658-665. doi:10.56434/j.arch.esp.urol.20247706.90 
  • Tim S, Mazur-Bialy AI. Physiotherapy interventions in the treatment of pelvic floor dysfunctions after gynaecological oncology procedures: a systematic review. J Gynecol Obstet Hum Reprod. Published online October 27, 2023. doi:10.1016/j.jogoh.2023.102688 
  • Matos SRL, Lucas Rocha Cunha M, Podgaec S, Weltman E, Yamazaki Centrone AF, Cintra Nunes Mafra AC. Consensus for vaginal stenosis prevention in patients submitted to pelvic radiotherapy. PLoS One. 2019;14(8):e0221054. Published 2019 Aug 9. doi:10.1371/journal.pone.0221054 
  • Wolin KY, Schwartz AL, Matthews CE, Courneya KS, Schmitz KH. Implementing the exercise guidelines for cancer survivors. J Support Oncol. 2012;10(5):171-177. doi:10.1016/j.suponc.2012.02.001 
  • (CYR2) Cyr MP, Dostie R, Camden C, et al. Improvements following multimodal pelvic floor physical therapy in gynecological cancer survivors suffering from pain during sexual intercourse: Results from a one-year follow-up mixed-method study. PLoS One. 2022;17(1):e0262844. Published 2022 Jan 25. doi:10.1371/journal.pone.0262844 
  • Shu T, Ren D, Wang R. The role of vacuum erection device and penile traction therapy in the patients after radical prostatectomy: a narrative review. Int J Impot Res. Published online May 29, 2025. doi:10.1038/s41443-025-01092-9 
  • Vitorino CN, Omodei MS, de Souza RC, et al. Assessment of sexual function in postmenopausal breast cancer survivors. Sex Med. 2024;12(3):qfae035. Published 2024 Jun 28. doi:10.1093/sexmed/qfae035 
  • Agrawal LS, O'Riordan L, Natale C, Jenkins LC. Enhancing Sexual Health for Cancer Survivors. Am Soc Clin Oncol Educ Book. 2025;45(3):e472856. doi:10.1200/EDBK-25-472856 
  • Facondo G, Bottero M, Goanta L, et al. Incidence and predictors of lower extremity lymphedema after postoperative radiotherapy for prostate cancer. Radiat Oncol. 2025;20(1):41. Published 2025 Mar 18. doi:10.1186/s13014-025-02599-7 
  • Hayes SC, Janda M, Ward LC, et al. Lymphedema following gynecological cancer: Results from a prospective, longitudinal cohort study on prevalence, incidence and risk factors. Gynecol Oncol. 2017;146(3):623-629. doi:10.1016/j.ygyno.2017.06.004 
  • Raj S, Prasad RR, Ranjan A. Incidence of vaginal toxicities following definitive chemoradiation in intact cervical cancer: A meta-analysis. J Contemp Brachytherapy. 2024;16(3):241-256. doi:10.5114/jcb.2024.141402 
  • Bowie J, Brunckhorst O, Stewart R, Dasgupta P, Ahmed K. Body image, self-esteem, and sense of masculinity in patients with prostate cancer: a qualitative meta-synthesis. J Cancer Surviv. 2022;16(1):95-110. doi:10.1007/s11764-021-01007-9 
  • Plinsinga ML, Rye S, Jones T, et al. Mild symptoms matter: Results from a prospective, longitudinal study on the relationship between symptoms, lymphedema and health-related outcomes post-gynecological cancer. Gynecol Oncol. 2024;191:158-164. doi:10.1016/j.ygyno.2024.10.011 
  • Sopfe J, Gupta A, Appiah LC, Chow EJ, Peterson PN. Sexual Dysfunction in Adolescent and Young Adult Survivors of Childhood Cancer: Presentation, Risk Factors, and Evaluation of an Underdiagnosed Late Effect: A Narrative Review. J Adolesc Young Adult Oncol. 2020;9(5):549-560. doi:10.1089/jayao.2020.0025 
  • Janssen SHM, Vlooswijk C, Bijlsma RM, et al. Health-related quality of life of long-term adolescent and young adult (AYA) cancer survivors compared to a matched normative population: results of the SURVAYA study. J Cancer Surviv. Published online June 17, 2025. doi:10.1007/s11764-025-01818-0